How the Epidermal Growth Factor Receptor family of tyrosine kinase receptors is involved in signalling in normal and diseased cells (e.g. cancer). Investigating the conformational structure of each of the receptors, when they interact and when they interact with other receptors in the family. Studying their interaction with the cell membrane, cytoskeleton and downstream signalling molecules, and the effects of therapeutic drugs targeted to these receptors at the molecular level.

Background

PhD in Biology - University of York. Title: Pleiotrophin and oligodendrocyte process extension and motility.

MSC Biomedical Sciences- University of Wolverhampton

General

Sarah has been with STFC since 2005 and joined the LSF in 2008. Sarah is currently a postdoctoral research assistant working on the BBSRC LoLa grant, Supra-molecular rules in signalling networks: A single molecule comparative study in cells and tissues. Is a member of the Biochemical Society.